Could you send us a demo project which demonstrates the issue? If yes, please send the project with description of the problem to support@vintasoft.com
Current version of SDK creates TIFF files with JPEG compression in RGB color space. We will add ability to create TIFF files with JPEG compression in Grayscale color space in 1 week.
VintaSoftTwain.NET SDK can be used for developing a remote scanning application. In this case you need to develop client-server application, please see our TWAIN Client-Server Demo here: http://www.vintasoft.com/vstwain-dotnet-examples.html